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Diabetic Foot: Understanding, Preventing, and Treating Complications

Protect your feet, protect your life: Learn how to prevent and manage diabetic foot complications

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By Janik Sundstrom
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Edited by Caitlin Snethlage

Published December 15, 2024.

a diagram of a foot with a red dot on it

Diabetes mellitus is a complex chronic condition that poses significant challenges to human health, with diabetic foot emerging as one of its most devastating potential complications.

As the global prevalence of diabetes continues to rise, understanding and preventing diabetic foot complications is becoming increasingly important. Each year, thousands of individuals face life-altering medical interventions due to these complications, highlighting the importance of comprehensive care and proactive management.

» Support your diabetic feet with custom orthotics for optimal comfort

What is Diabetic Foot?

Diabetic foot is a serious complication of diabetes that can lead to severe foot problems.

These include:

  1. Impaired Quality of Life: Diabetic foot can significantly impact a person's quality of life, limiting mobility, causing pain, and increasing the risk of hospitalization.
  2. Chronic Ulcers: Nerve damage and poor circulation can cause even minor injuries to develop into chronic, non-healing ulcers.
  3. Infection: Open wounds are susceptible to infection, spreading rapidly and leading to serious complications.
  4. Amputation: In severe cases, infection can spread to the bone, requiring amputation to prevent the spread of disease. Annually, over 60,000 amputations are performed in the U.S. due to diabetes-related complications.

The severity of diabetic foot complications is classified using the Wagner Ulcer Classification System:

Grade 0: Intact skin with underlying bony deformities.

Grade 1: Superficial ulcer.

Grade 2: Deep ulcer extending into subcutaneous tissue.

Grade 3: Deep ulcer with abscess or osteomyelitis.

Grade 4: Partial foot gangrene.

Grade 5: Extensive foot gangrene.

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What Causes Diabetic Foot?

Diabetic foot is a complex process caused by two primary physiological changes that happen in individuals with long-standing diabetes. These mechanisms work together to create a perfect storm of potential complications that compromise foot health and function.

1. Diabetic Neuropathy

The delicate nerve networks responsible for sensation deteriorate when blood sugar levels persist. This insidious condition, known as diabetic neuropathy, primarily affects the feet.

Key symptoms of diabetic neuropathy include:

  • Loss of Sensation: A significant consequence of diabetic neuropathy is the gradual loss of foot sensation. This can make it difficult to detect injuries, such as cuts, blisters, or foreign objects, leading to serious infections.
  • Muscle Weakness: Nerve damage can weaken the muscles in the feet, affecting balance, coordination, and the ability to walk normally. This altered gait can lead to abnormal pressure points, increasing the risk of foot ulcers and deformities.
  • Altered Reflexes: Impaired reflexes can contribute to balance problems and increase the risk of falls and injuries.

Research indicates that approximately 50% of individuals with long-term diabetes will experience some form of neuropathy, making it a pervasive and significant concern.

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2. Peripheral Vascular Disease

Accompanying neuropathy, peripheral vascular disease further compounds the risks faced by individuals with diabetes. This condition significantly reduces blood flow to the feet, creating an environment where healing becomes increasingly tricky.

Key consequences of PVD:

  • Impaired Healing: Reduced blood flow hampers the body's ability to repair tissues, making even minor wounds prone to infection.
  • Tissue Death: In severe cases, lack of blood flow can lead to tissue death (gangrene), which could result in amputation.
  • Increased Infection Risk: Poor circulation weakens the body's defense against infection, making it easier for bacteria to invade.

Approximately 15% of diabetic foot cases are directly attributed to PVD, underscoring its critical role in the development of complications.

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Symptoms of Diabetic Foot

Early detection of diabetic foot complications is critical for preventing serious outcomes. Patients should be vigilant about several key warning signs that indicate potential problems:

  1. Numbness or Tingling: This is often the first sign of diabetic neuropathy. The loss of sensation can make it difficult to detect injuries, such as cuts or blisters, which can lead to serious infections.
  2. Altered Temperature Sensation: People with diabetic neuropathy may have difficulty feeling extreme temperatures. This can lead to accidental burns or frostbite, especially in the feet.
  3. Redness and Inflammation: Redness, swelling, and warmth in the foot or ankle are signs of infection. If not treated promptly, these infections can quickly spread and become serious.
  4. Dry, Cracked Skin: Nerve damage can affect the sweat glands, leading to dry, cracked skin. This can increase the risk of infection, especially in areas like the heels.
  5. Calluses or Corns: These are areas of thickened skin that develop due to pressure or friction. Poor circulation and nerve damage in people with diabetes can make it harder for these calluses to heal, increasing the risk of infection.
  6. Poor Wound Healing: High blood sugar levels can impair the body's ability to heal wounds. Even minor cuts or blisters can take longer to heal, increasing the risk of infection and ulceration.
  7. Foot Deformities: Over time, nerve damage can weaken the muscles in the feet, leading to foot deformities such as hammertoes or claw toes. These deformities can put additional pressure on the feet, increasing the risk of ulcers.

» Learn about the difference between corns and bunions

Preventing Diabetic Foot with Glycemic Control

Glycemic control is a cornerstone of diabetes management. It refers to keeping blood glucose levels within a healthy range. By maintaining optimal blood sugar levels, individuals with diabetes can significantly reduce their risk of developing diabetic foot and other serious complications.

Key strategies for glycemic control include:

  1. Self-Monitoring of Blood Glucose: Regular blood glucose testing helps individuals understand their blood sugar patterns and adjust their diet, medication, and exercise routines.
  2. Continuous Glucose Monitoring (CGM): CGM systems provide real-time glucose data, enabling more precise blood sugar management.
  3. Balanced Diet: A diet rich in fruits, vegetables, whole grains, and lean proteins can help stabilize blood sugar levels. Limiting the intake of sugary foods and refined carbohydrates is crucial.
  4. Regular Exercise: Physical activity improves insulin sensitivity, making it easier to control blood sugar. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  5. Quit Smoking: Smoking can worsen blood circulation and increase the risk of complications.
  6. Medication Adherence: Taking prescribed medications, such as oral or insulin, as directed is essential for maintaining blood sugar control.

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Preventing Diabetic Foot through Lifestyle

While glycemic control is undoubtedly crucial, it's essential to recognize that a holistic approach is necessary for comprehensive diabetic foot care. Lifestyle choices are pivotal in managing and potentially preventing this condition, representing the first and most powerful line of defense.

Beyond prevention, these lifestyle modifications can also be instrumental in treating existing diabetic foot complications.

Nutrition

Diet is more than a method of controlling blood sugar—it's a comprehensive approach to whole-body health. Complex carbohydrates, lean proteins, and anti-inflammatory foods become medicinal tools that support cellular repair, regulate insulin response, and enhance overall metabolic resilience.

Key nutritional strategies include:

  • Prioritizing low glycemic index foods
  • Incorporating omega-3 fatty acids to reduce inflammation
  • Consuming foods rich in antioxidants to support cellular health

» Check out the top vitamins to boost foot health

Exercise

Physical activity is more than a health recommendation—it's a potent metabolic reset button. Each step and repetition becomes a targeted intervention that reshapes how your body processes glucose, manages insulin and maintains circulatory health.

Different exercise modalities offer unique benefits:

  • Cardiovascular exercises improve peripheral circulation
  • Strength training enhances insulin sensitivity
  • Flexibility work supports joint health and reduces injury risk
Even modest exercise routines can create significant improvements in overall metabolic health.

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Stress Management

Chronic stress triggers a cascade of hormonal responses that can devastate blood sugar control. Cortisol and adrenaline surge, creating metabolic chaos that undermines even the most rigorous diabetes management strategies. Mindfulness practices are critical medical interventions rather than optional wellness techniques.

Daily Foot Care

Diabetic patients are encouraged to check their feet daily to identify potential problems early on, such as:

  • Skin changes: Redness, swelling, or discoloration
  • Sores or ulcers: Open wounds, blisters, or cuts
  • Infections: Signs of pus, odor, or increased pain

Regular foot care is essential for preventing these complications. Here are some key tips:

  • Moisturize daily: Keep your skin soft and supple by applying lotion to your entire foot, but avoid between the toes.
  • Trim your nails carefully: Using a clean clipper, cut your toenails straight across. Never cut them too short or round the edges, which can lead to ingrown toenails and infections.
  • Wash your feet gently: Wash your feet daily with lukewarm water and a mild soap. Dry them thoroughly, especially between the toes.
  • Choose the right footwear: Wear well-fitting shoes that provide adequate support and cushioning. Avoid tight shoes or shoes with seams that can irritate your feet.

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Physical Therapy

Physical therapy is essential for restoring strength, mobility, and balance in patients who have undergone conservative or surgical interventions for foot conditions. Therapists focus on rebuilding lower limb strength to pre-injury levels through targeted exercises and provide gait retraining.

In some cases, patients may need to reduce weight-bearing on the affected area to facilitate healing, and physical therapists can guide them in using assistive devices like crutches and teach alternative walking techniques.

» Try these exercises for peripheral neuropathy relief

Custom Orthotics

Custom orthotics are specialized devices designed to correct biomechanical imbalances and support the foot and ankle. They are particularly beneficial for individuals with diabetic foot, as they can help:  

  • Reduce Pressure: By distributing weight more evenly across the foot, orthotics can alleviate pressure on specific areas and reduce the risk of pressure ulcers.  
  • Improve Gait: Orthotics can help correct abnormal gait patterns, reducing stress on the feet and ankles.  
  • Enhance Comfort: Custom-made orthotics are designed to fit the foot's unique shape, providing optimal comfort and support.  


Professional Medical Monitoring

Regular medical check-ups are vital for individuals with diabetes. Healthcare providers can conduct crucial assessments, such as monofilament testing to evaluate nerve sensation and Doppler ultrasound to assess blood circulation. Early detection of potential issues is key to preventing serious complications.

Remember, listening to your healthcare provider's advice and adhering to recommended treatment plans is essential in managing diabetic foot and ensuring optimal foot health.

Treating Diabetic Foot

When diabetic foot complications arise, a multidisciplinary approach is essential. This typically involves a team of healthcare professionals, including:

  • Endocrinologists: To manage blood sugar levels and overall diabetes care.
  • Podiatrists: To specialize in foot care and address specific foot problems.
  • Vascular Specialists: To treat vascular issues, such as poor circulation.
  • Wound Care Specialists: To manage and treat ulcers and infections.

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Several advanced diagnostic tools are used to assess the severity of diabetic foot complications:

  • Doppler Ultrasound: This non-invasive test measures blood flow in the arteries and veins of the feet. Reduced blood flow can impair healing and increase the risk of infection.
  • Infrared Thermography: This technique measures skin temperature and indicates areas of reduced blood flow. Cooler regions may be more susceptible to tissue breakdown and ulceration.
  • Monofilament Testing: This simple test assesses nerve sensation in the feet. Reduced sensation can make detecting and treating injuries difficult, increasing the risk of complications.

By combining these diagnostic tools and a multidisciplinary approach, healthcare providers can effectively diagnose and treat diabetic foot complications, reducing the risk of serious consequences like amputation.

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The Best Approach Is A Proactive One

Diabetic foot is a serious yet manageable condition. Like diabetes, maintaining foot health requires ongoing vigilance and proactive care. It’s critical to recognize that foot complications often develop gradually, frequently without obvious pain or noticeable symptoms.

The goal isn’t just to fix problems as they come up but to build a system that helps prevent serious complications from happening in the first place. Diabetic foot care is about staying on top with regular check-ins, understanding the risks, and taking small steps early to keep everything on track.

» Experience the difference of custom orthotics for preventing diabetic foot



Disclaimer: The information on this blog is for educational purposes only and is not a substitute for professional medical advice. Upstep does not provide medical diagnosis or treatment. While qualified podiatrists create our content, it's essential to consult with your healthcare provider for any foot or ankle concerns you may have.