Can running aggravate Morton's Neuroma?

Yes, an activity like running can exacerbate Morton's neuroma.

High-intensity exercise causes a repeated increase in pressure that will worsen the neuroma.

But this does not necessarily mean you have to stop running.

Custom orthotics will significantly help as they minimize the plantar pressure on the foot by cushioning it. This will allow your foot room to heal without having to give up running.

The best type of orthotics are those custom-designed for running. You can read this informative review of Upstep's running custom orthotics to see how they work and the benefits they offer.

No and Yes. Morton’s neuroma is caused by thickening of tissue around the interdigital nerves. So no because running is causative agent and also aggravates the thickening. This Increases pressure/compression on the interdigital nerve leading to sharp/burning pain. Yes because you can wear custom made orthotics when running to cushion against excessive pressure. Orthotics also help correct faulty gait biomechanics.

You're right to be careful. Potentially, running and any other high-impact activity can subject your foot to repeated trauma when you have Morton's neuroma. However, you can continue running despite the neuroma by using the right foot support and toe separators to reduce any excess pressure and manage symptoms.

Running can aggravate Morton's neuroma because of the repeated pressure on your toes. It may be better to take a break to allow your toes some time to heal. However, if you have to run, ensure you use shoes with wide toe spaces. You can also cushion the shoe with orthotics to minimize the pressure.